Noisy silencing of chromatin.


Rando, O. J. ; Paulsson, J. Noisy silencing of chromatin. Developmental Cell 2006, 11, 134-6.

Date Published:

2006 Aug


Chromatin-based repression is a major mechanism for epigenetically heritable variation. Work in the July 21 issue of Molecular Cell quantitatively examines transcriptional silencing in individual yeast cells, demonstrating locus-specific effects and finding that different silencing mutants exhibit qualitatively distinct single-cell defects.

Last updated on 11/21/2018